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    The skin ac lesions noticed were symmetrical erythematous dermatitis of the hands, feet, face, and neck; the demarcation lines showed a raised edge. Xo affection of bladder or rectum: acne. There was no distinction of in age, race, or acclimatization among those attacked.

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    He also regretted the lack of that almost universal cooperation between physicians and pharmacists that formerly existed, and which is stretch now largely responsible for the common use of fixed formula; and compressed tablets. The initial fever is, the author believes, as regular in its course as that of most of the other zymotic fevers, although its duration is difficult of determination because, like some of the other fevers having a similar type, the secondary fever supervenes or overlaps on the primary, tretinoin without the occurrence of a distinct remission.

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